Prediabetes as a risk factor for stress induced hyperglycemia in non diabetic critically ill adult

Introduction Hyperglycemia in critically ill patients has not shown predict poor outcomes in those with preexisting Diabetes Mellitus (DM). Otherwise hyperglycemia in patients without DM has shown poor outcomes and generally this association reflects the severity of the disease. In addition the high level of glycemia can produce deleterious effects and is associated inversely to the survival. Also, It has been shown that insulin has anti-inflammatory effects, and hyperinsulinism can predicts survival in experimental critically ill models. Nevertheless is not known if prediabetic patients (A subgroup of non-diabetic patients that often presents insulin resistance and hyperinsulinism) have an increased risk of stress induced hyperglycemia.